Drug-induced diabetes mellitus

@article{Izzedine2005DruginducedDM,
  title={Drug-induced diabetes mellitus},
  author={Hassane Izzedine and Vincent Launay-Vacher and Camille Deybach and Edward Bourry and Beno{\^i}t Barrou and Gilbert Deray},
  journal={Expert Opinion on Drug Safety},
  year={2005},
  volume={4},
  pages={1097 - 1109}
}
Aims: To review the medications that influence glucose metabolism with a focus on hypertensive, transplant and HIV-infected patient populations. Methods: Literature obtained from a MEDLINE search from 1970 to present, including studies published in the English language. The search strategy linked drugs, hyperglycaemia and diabetes mellitus, HIV, transplantation, hypertension and psychiatric patients. Results: Many common therapeutic agents influence glucose metabolism. Multiple mechanisms of… 
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43 Citations
Highly Influential Citations
1
Background Citations
10
Results Citations
2

43 Citations

Drug-induced hyperglycaemia and diabetes: pharmacogenomics perspectives
TLDR
The genetic basis of drug-induced diabetes is elucidated and the way for the precise use of these drugs in the clinic is paved, including calcineurin inhibitors, antipsychotics, hormones, and antihypertensive drugs.
CORRELATION OF ANTIHYPERTENSIVE DRUGS AND NEW ONSET DIABETES: A REVIEW
Assessment of Plasma level of Nesfatin-1 in newly diagnosed Type 2 Diabetic patients
TLDR
The novelty of this study is that it showed, for the first time, significantly lower nesfatin-1 levels in diabetic patients but less lower in prediabetic patients (IGT).
Hypertension in Children with the Metabolic Syndrome or Type 2 Diabetes
TLDR
A comprehensive approach, including non-pharmacologic measures, hypoglycemic and antihypertensive medications, and perhaps even bariatric surgery in selected patients, is indicated in order to reduce future cardiovascular risk.
Hyperglycemia related to high-dose glucocorticoid use in noncritically ill patients
TLDR
High-dose prednisone for 2 to 3 months produced an elevated incidence of diabetes, usually with mild hyperglycemia occurring between the second and fourth week, normalizing spontaneously in all cases.
Adverse Metabolic Effects Associated with Atypical Antipsychotics
TLDR
There are no large controlled trials published quantifying the prevalence of adverse effects on glucose-insulin homeostasis and lipid metabolism in patients receiving atypical antipsychotics, so recommendations for prevention and treatment of the adverse metabolic effects are outlined.
Antipsychotics-induced metabolic alterations: Focus on adipose tissue and molecular mechanisms
Management of hypertension in children and adolescents with the metabolic syndrome.
TLDR
Several aspects of the approach to treatment of hypertension in young patients with the metabolic syndrome are highlighted, including the definition of hypertension, use of nonpharmacologic measures, indications for instituting antihypertensive medications, and the potential adjunctive role that insulin-sensitizing agents may play in blood pressure reduction.
Drug-induced diabetes type 2: In silico study involving class B GPCRs
TLDR
The study showed that incretin hormone receptors, named also gut hormone receptors as they are expressed in the gastrointestinal tract, could potentially act as unintended targets for orally administrated drugs and suggested that those strongly binding molecules could potentially stimulate GIPR and GLP1R and/or inhibit GCGR which could lead to increased insulin secretion and decreased hepatic glucose production.
Evaluation of admission glucose profile and glycosylated hemoglobin: factors associated with glucose metabolism should be assessed.
TLDR
It could be concluded that AGP and HbA1c have not sufficient power to screen and predict short-term cardiac complications after AMI, and AGP is a good predictor for AMI complications, significantly better for electrical complications.
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References

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TLDR
This review examines medications that may alter glucose insulin homeostasis and discusses possible mechanisms of action at the potential sites at which medication may induce changes in glucose metabolism.
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TLDR
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TLDR
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