Drug-drug interactions of triazole antifungal agents in multimorbid patients and implications for patient care.

@article{Nivoix2009DrugdrugIO,
  title={Drug-drug interactions of triazole antifungal agents in multimorbid patients and implications for patient care.},
  author={Yasmine Nivoix and Genevi{\`e}ve Ubeaud-S{\'e}quier and Pauline Engel and Dominique Lev{\^e}que and Raoul Herbrecht},
  journal={Current drug metabolism},
  year={2009},
  volume={10 4},
  pages={395-409}
}
Drug interactions occur frequently with triazole antifungal agents because of their properties as inhibitors of 1 or more phase 1 (cytochrome P450) biotransformation enzymes and, possibly, as inhibitors or substrates of a phase 2 biotransformation enzyme or transporter protein. Multimorbid patients, including those with hematologic malignancies or other cancers, hematopoietic stem cell or organ transplant recipients, patients infected with the human immunodeficiency virus, and those in the… CONTINUE READING

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