Drug-drug interactions in a geriatric outpatient cohort: prevalence and relevance.

  title={Drug-drug interactions in a geriatric outpatient cohort: prevalence and relevance.},
  author={Linda R. Tulner and Suzanne V Frankfort and George J P T Gijsen and Jos P M C van Campen and Cornelis H. W. Koks and Jos H. Beijnen},
  journal={Drugs & aging},
  volume={25 4},
BACKGROUND The prevalence of drug-drug interactions (DDIs) in a geriatric population may be high because of polypharmacy. However, wide variance in the clinical relevance of these interactions has been shown. OBJECTIVES To explore whether adverse drug reactions (ADRs) as a result of DDIs can be identified by clinical evaluation, to describe the prevalence of ADRs and diminished drug effectiveness as a result of DDIs and to verify whether the top ten most frequent potential DDIs known to… CONTINUE READING

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