Drug-drug interactions between HMG-CoA reductase inhibitors (statins) and antiviral protease inhibitors.

@article{Chauvin2013DrugdrugIB,
  title={Drug-drug interactions between HMG-CoA reductase inhibitors (statins) and antiviral protease inhibitors.},
  author={Beno{\^i}t Chauvin and Sylvain Drouot and Aur{\'e}lie Barrail-Tran and A -M. Taburet},
  journal={Clinical pharmacokinetics},
  year={2013},
  volume={52 10},
  pages={
          815-31
        }
}
The HMG-CoA reductase inhibitors are a class of drugs also known as statins. These drugs are effective and widely prescribed for the treatment of hypercholesterolemia and prevention of cardiovascular morbidity and mortality. Seven statins are currently available: atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin and simvastatin. Although these drugs are generally well tolerated, skeletal muscle abnormalities from myalgia to severe lethal rhabdomyolysis can occur… CONTINUE READING
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