Drug disruption of short-term memory in Drosophila melanogaster.

  title={Drug disruption of short-term memory in Drosophila melanogaster.},
  author={S. Z. Xia and Li Liu and Chao Feng and Ai-li Guo},
  journal={Pharmacology, biochemistry, and behavior},
  volume={58 3},
Recent work on operant visual learning and memory in Drosophila has suggested at least three distinct memory phases. Trying to disrupt memory pharmacologically, we fed flies with ouabain or the depolarizing drugs potassium chloride (KCl), lithium chloride (LiCl) and monosodium glutamate for some specific time before training. The depolarizing drugs abolished memory very soon after training. Ouabain exerted no effect on memory within the first 20 min but abolished it more than 30 min after… CONTINUE READING

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