Drug discovery: Playing dirty

  title={Drug discovery: Playing dirty},
  author={Simon T Frantz},
942 not as specific as its creators had thought. The drug works by attaching to a key part of an overactive protein that causes chronic myeloid leukaemia. In his lecture, Druker revealed that the drug also inhibits a second protein, known as the PDGF receptor. Sitting in the audience, Heinrich had a brainwave. At the time, he was working on a protein similar to PDGF called KIT. “We became interested in the idea that Gleevec could probably inhibit KIT as well,” he says. Working with a team led… CONTINUE READING
102 Citations
0 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 102 extracted citations

Similar Papers

Loading similar papers…