Drug discontinuations in the United Kingdom and the United States, 1964 to 1983: Issues of safety

@article{Bakke1984DrugDI,
  title={Drug discontinuations in the United Kingdom and the United States, 1964 to 1983: Issues of safety},
  author={Olav M. Bakke and William M. Wardell and Louis Lasagna},
  journal={Clinical Pharmacology \& Therapeutics},
  year={1984},
  volume={35}
}
Since the modern era of drug regulation began in the early 1960s, fewer new drugs have been approved for marketing in the United States than in the United Kingdom. We examined whether information can be obtained about the relative safety of higher and lower introductory rate policies by comparing each country's record of drugs that have been discontinued (removed from the market, withdrawn, or whose licenses were allowed to lapse) while a question of safety existed. We have compiled a list of… 
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