Drug development for stroke: importance of protecting cerebral white matter.

@article{Dewar1999DrugDF,
  title={Drug development for stroke: importance of protecting cerebral white matter.},
  author={Deborah Dewar and Philippa S. Yam and J Mcculloch},
  journal={European journal of pharmacology},
  year={1999},
  volume={375 1-3},
  pages={41-50}
}
Multiple pharmacological mechanisms have been identified over the last decade which can protect grey matter from ischaemic damage in experimental models. A large number of drugs targeted at neurotransmitter receptors and related mechanisms involved in ischaemic damage have advanced to clinical trials in stroke and head injury based on their proven ability to reduce grey matter damage in animal models. The outcome to date of the clinical trials of neuroprotective drugs has been disappointing… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…