Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy.

@article{Iiizumi2008DrugDA,
  title={Drug development against metastasis-related genes and their pathways: a rationale for cancer therapy.},
  author={Megumi Iiizumi and Wen Liu and S. K. Pai and E. Furuta and K. Watabe},
  journal={Biochimica et biophysica acta},
  year={2008},
  volume={1786 2},
  pages={
          87-104
        }
}
It is well recognized that the majority of cancer related deaths is caused by metastatic diseases. Therefore, there is an urgent need for the development of therapeutic intervention specifically targeted to the metastatic process. In the last decade, significant progress has been made in this research field, and many new concepts have emerged that shed light on the molecular mechanism of metastasis cascade which is often portrayed as a succession of six distinct steps; localized invasion… Expand
Why does cancer therapy lack effective anti-metastasis drugs?
Genomic analysis of invasion-metastasis-related factors in pancreatic cancer cells.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 276 REFERENCES
Translational approaches using metastasis suppressor genes
KISS1 metastasis suppression and emergent pathways
The role of tumor metastasis suppressors in cancers of breast and prostate.
Cancer spread and micrometastasis development: Quantitative approaches for in vivo models
...
1
2
3
4
5
...