Drug delivery to the posterior segment of the eye: some insights on the penetration pathways after subconjunctival injection.

@article{Lee2001DrugDT,
  title={Drug delivery to the posterior segment of the eye: some insights on the penetration pathways after subconjunctival injection.},
  author={Thomas Wai-Yip Lee and Joseph R. Robinson},
  journal={Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  year={2001},
  volume={17 6},
  pages={565-72}
}
The aim of this study is to gain an understanding of the penetration pathways for a drug to enter the posterior segment of the eye after subconjunctival injection. 14C-mannitol was injected subconjunctivally, and 14C-mannitol and 14C-inulin were injected intracamerally. The aqueous and vitreous levels were determined at selected time points. The results of subconjunctival injection and intracameral injection were compared. The vitreous level of the dosed eye is much higher than that of the… CONTINUE READING

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