Drug delivery systems for fluoroquinolones: New prospects in tuberculosis treatment

@article{LeDeygen2017DrugDS,
  title={Drug delivery systems for fluoroquinolones: New prospects in tuberculosis treatment},
  author={Irina M Le-Deygen and Anna A Skuredina and Elena V. Kudryashova},
  journal={Russian Journal of Bioorganic Chemistry},
  year={2017},
  volume={43},
  pages={487-501}
}
The review focuses on new delivery systems of fluoroquinolones, the highly active antibiotics, the therapeutic application of which is still limited due to low bioavailability and low solubility in biological media. The development of suitable delivery systems seems to be a promising solution to these problems. Here, we consider the delivery systems based on synthetic polymers (polylactic and polyglycolic acids and their copolymers, polycaprolactones, etc.) and natural polymers, in particular… CONTINUE READING
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