Drug delivery optimization through Bayesian networks.

  title={Drug delivery optimization through Bayesian networks.},
  author={Riccardo Bellazzi},
  journal={Proceedings. Symposium on Computer Applications in Medical Care},
  • Riccardo Bellazzi
  • Published 1992 in
    Proceedings. Symposium on Computer Applications…
This paper describes how Bayesian Networks can be used in combination with compartmental models to plan Recombinant Human Erythropoietin (r-HuEPO) delivery in the treatment of anemia of chronic uremic patients. Past measurements of hematocrit or hemoglobin concentration in a patient during the therapy can be exploited to adjust the parameters of a compartmental model of the erythropoiesis. This adaptive process allows more accurate patient-specific predictions, and hence a more rational dosage… CONTINUE READING