Drug delivery: Stealth particles give mucus the slip.

@article{Cu2009DrugDS,
  title={Drug delivery: Stealth particles give mucus the slip.},
  author={Yen Cu and W. Mark Saltzman},
  journal={Nature materials},
  year={2009},
  volume={8 1},
  pages={11-3}
}
Mucus, the amorphous, sticky substance that often invokes unpleasant images, may not be a favourite topic at the dinner table, but we all rely on it for a healthy life. The mucus barrier is essential in preventing viruses and bacteria from entering our tissues; but this function also poses a perennial problem for drug delivery (Fig. 1). Ying-Ying Wang and colleagues have now demonstrated a method that could help drug-loaded nanoparticles to slip through the mucus barrier1. Their coating of a… CONTINUE READING
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This approach mimics the properties of virus particles that are known to infect mucosal tissues

  • Mosqueira, C V.
  • Pharm. Res
  • 2008

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