Drug confirmation by mass spectrometry: Identification criteria and complicating factors.

@article{Yuan2015DrugCB,
  title={Drug confirmation by mass spectrometry: Identification criteria and complicating factors.},
  author={C. Yuan and Derrick J Chen and S. Wang},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2015},
  volume={438},
  pages={
          119-25
        }
}
Drug confirmation by mass spectrometry coupled with chromatography is essential to toxicology, doping control, pain management, and workplace drug testing. High confidence in this technology is due to its superior specificity and sensitivity. However, there are challenges associated with drug confirmation, and proper setup and validation of these assays are important in assuring high-quality results. In this article, assay parameters required for drug confirmation are summarized based on recent… Expand
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