Drug-associated non-pyrogenic hyperthermia: a narrative review

@article{Bongers2019DrugassociatedNH,
  title={Drug-associated non-pyrogenic hyperthermia: a narrative review},
  author={Koen Sebastiaan Bongers and Mohammed Saji Salahudeen and Gregory Mark Peterson},
  journal={European Journal of Clinical Pharmacology},
  year={2019},
  volume={76},
  pages={9-16}
}
Purpose Hyperthermia occurs when heat accumulation surpasses the body’s ability for heat dissipation. Many drugs may affect thermoregulation. This narrative review aimed to provide an overview of the current literature concerning reports of drug-associated non-pyrogenic hyperthermia. Methods A comprehensive search was performed across 5 databases covering the period of inception to March 2019, for publications that reported hyperthermia associated with drug use. Studies that reported potential… 

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TLDR
Although the recognition of causative agents is increasing, the treatment of drug-induced hyperthermia remains unchanged and continues to be primarily supportive.

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Drugs that impair thermoregulation are frequently encountered in patients admitted for heatstroke, and patients taking such drugs may experience increased morbidity over those patients not takingsuch drugs.

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A review of the common classes of drugs that can induce hyperthermia, highlighting the deleterious effects of a sustained high temperature and outlining available treatments is outlined.

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TLDR
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