Drug adherence in patients taking oral anticoagulation therapy

  title={Drug adherence in patients taking oral anticoagulation therapy},
  author={Sebastian Ewen and Volker Rettig-Ewen and Felix Mahfoud and Michael B{\"o}hm and Ulrich Laufs},
  journal={Clinical Research in Cardiology},
Oral anticoagulation has proven to reduce mortality and morbidity of thromboembolic events. One of the most important determinants of the effectiveness and safety of anticoagulation therapy is the adherence to the prescribed therapy. Vitamin K antagonists are characterized by under-utilization, a narrow therapeutic window and multiple food and drug interactions which contribute to a variable dose–response relationship with the risk of insufficient protection and/or increased bleeding risk. The… CONTINUE READING
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