Drug Susceptibility of Mycobacterium tuberculosis Beijing Genotype and Association with MDR TB

@inproceedings{Steenwinkel2012DrugSO,
  title={Drug Susceptibility of Mycobacterium tuberculosis Beijing Genotype and Association with MDR TB},
  author={Jurriaan E. M. de Steenwinkel and Marian T. ten Kate and Gerjo J. de Knegt and Kristin Kremer and Rob Edward Aarnoutse and Martin J. Boeree and Henri A. Verbrugh and Dick van Soolingen and Irma A. J. M. Bakker-Woudenberg},
  booktitle={Emerging infectious diseases},
  year={2012}
}
To determine differences in the ability of Mycobacterium tuberculosis strains to withstand antituberculosis drug treatment, we compared the activity of antituberculosis drugs against susceptible Beijing and East-African/Indian genotype M. tuberculosis strains. Beijing genotype strains showed high rates of mutation within a wide range of drug concentrations, possibly explaining this genotype's association with multidrug-resistant tuberculosis. 
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