Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Probably Induced by a Lamotrigine–Ginseng Drug Interaction

@article{Myers2015DrugRW,
  title={Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome Probably Induced by a Lamotrigine–Ginseng Drug Interaction},
  author={Amy P Myers and T. Watson and Steven B Strock},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2015},
  volume={35}
}
  • Amy P Myers, T. Watson, Steven B Strock
  • Published 2015
  • Medicine
  • Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
  • The likelihood of a drug reaction with lamotrigine is increased by dose escalation that is too rapid or drug interactions that increase the concentration of lamotrigine. There is a well‐documented interaction between valproic acid and lamotrigine in which lamotrigine levels are increased, subsequently increasing the risk of a drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome. This syndrome is characterized by fever, lymphadenopathy, diffuse maculopapular rash, multivisceral… CONTINUE READING
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