Drug Peak Plasma Concentrations and Time to Peak in Each Subject 56 2 . 10 Cardiovascular Effect of Intravenously Administered Dyphylline


approved: Redacted for Privacy 0 James W. Ayres,(PV.D. Dyphylline has been shown to be rapidly and completely absorbed from oral tablets in an absolute bioavailability study. In a pilot study two healthy male subjects received 1000 mg of dyphylline via intravenous infuson at a rate of 50 mg/min (1.0 ml/min) for 20 minutes. Plasma samples were collected for… (More)


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