Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone

@article{Engel2007DrugIC,
  title={Drug Insight: clinical use of agonists and antagonists of luteinizing-hormone-releasing hormone},
  author={J{\"o}rg Bernhard Engel and Andrew V. Schally},
  journal={Nature Clinical Practice Endocrinology \&Metabolism},
  year={2007},
  volume={3},
  pages={157-167}
}
  • J. EngelA. Schally
  • Published 1 February 2007
  • Medicine, Biology
  • Nature Clinical Practice Endocrinology &Metabolism
This article reviews the clinical uses of agonists and antagonists of luteinizing-hormone-releasing hormone (LHRH), also known as gonadotropin-releasing hormone. In particular, the state of the art treatment of breast, ovarian and prostate cancer, reproductive disorders, uterine leiomyoma, endometriosis and benign prostatic hypertrophy is reported. Clinical applications of LHRH agonists are based on gradual downregulation of pituitary receptors for LHRH, which leads to inhibition of the… 

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  • Medicine, Biology
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