Drug Insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

@article{Reed2006DrugIC,
  title={Drug Insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms},
  author={John C. Reed},
  journal={Nature Clinical Practice Oncology},
  year={2006},
  volume={3},
  pages={388-398}
}
Cell death is a normal facet of human physiology, ensuring tissue homeostasis by offsetting cell production with cell demise. Neoplasms arise in part because of defects in physiological cell death mechanisms, contributing to pathological cell expansion. Defects in normal cell death pathways also contribute to cancer progression by permitting progressively… CONTINUE READING