Drug-Induced Liver Disease

@article{Zimmerman2012DrugInducedLD,
  title={Drug-Induced Liver Disease},
  author={Hyman J. Zimmerman},
  journal={Drugs},
  year={2012},
  volume={16},
  pages={25-45}
}
SummaryThe large number of chemical agents administered for therapeutic or diagnostic purposes can produce various types of hepatic injury by several mechanisms. Acute injury may be cytotoxic, cholestatic or mixed. Cytotoxic injury may consist of necrosis or steatosis. Cholestatic injury may be cholangiolitic (hepatocanalicular) or bland (canalicular). Chronic hepatic lesions caused by medicinal agents include chronic active hepatitis, steatosis, cirrhosis, fibrosis, hepatoportal sclerosis (non… Expand
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