Drug Holidays From ADHD Medication

  title={Drug Holidays From ADHD Medication},
  author={Kinda Ibrahim and Parastou Donyai},
  journal={Journal of Attention Disorders},
  pages={551 - 568}
Objective: ADHD is managed by stimulants that are effective but can cause growth retardation. Prescribers should ideally monitor children and trial a “drug holiday” to enable catch-up growth. Our aim was to map the experience of drug holidays from ADHD medication in children and adolescents. Method: A comprehensive search of the literature identified 22 studies published during the period 1972 to 2013. Results: Drug holidays are prevalent in 25% to 70% of families and are more likely to be… 

Caught in the eye of the storm: a qualitative study of views and experiences of planned drug holidays from methylphenidate in child and adolescent ADHD treatment.

Planned drug holidays could address premature treatment cessation by enabling adolescents to assess repercussions under medical supervision by allowing older children to self-assess their ability to manage without medication when they show signs of wanting to discontinue treatment prematurely.

Tolerance to Stimulant Medication for Attention Deficit Hyperactivity Disorder: Literature Review and Case Report

Further research is required to define clinical tolerance for stimulants in ADHD and to provide guidance on identifying and managing tolerance in clinical practice, as there are relatively few studies published.

The Construction and Validation of Child, Adolescent and Parental Decision Aids for Considering Methylphenidate Drug Holidays in ADHD

A suite of decision aids to help families decide if they want to take a drug holiday from methylphenidate are designed and developed and it is envisage these materials will open up the space to discuss drug holidays in ADHD during annual reviews, in line with UK government guidelines.

What stops practitioners discussing medication breaks in children and adolescents with ADHD? Identifying barriers through theory-driven qualitative research

  • K. IbrahimP. Donyai
  • Medicine, Psychology
    ADHD Attention Deficit and Hyperactivity Disorders
  • 2018
‘Education’ and ‘enablement’ interventions were identified as key activities targeting all three components, which could feasibly increase uptake of practitioner-initiated planned drug holidays from methylphenidate.

Intentional Discontinuation of Psychostimulants Used to Treat ADHD in Youth: A Review and Analysis

While confirming the ability of stimulants to treat ADHD in youth, the results support periodic consideration of trials of stopping medications to determine continued need and inform evidence-based guidelines for discontinuation.

ADHD in school-aged youth

This article will address special treatment considerations to aid in the management of attention-deficit/hyperactivity disorder in the primary care setting, including substance use disorders and diversion, cardiac issues and stimulant medication, medication holidays and follow-up monitoring.

Examining Breaks and Resistance in Medication Adherence Among Adolescents With ADHD as Associated With School Outcomes

Examination of school outcomes among adolescents with ADHD who take medication breaks versus resisting medication suggests that more positive school outcomes in terms of behaviors and grades are associated with adolescents taking breaks from their ADHD medication rather than resisting their medication.

The construction and validation of child , adolescent and parental decision aids for considering methylphenidate drug

A suite of decision aids to help families decide if they want to take a drug holiday from methylphenidate are designed and developed and it is envisage these materials will open up the space to discuss drug holidays in ADHD during annual reviews, in line with UK government guidelines.

Attention-Deficit/Hyperactivity Disorder Medication Use in Adolescents: The Patient's Perspective.



Growth on stimulant medication; clarifying the confusion: a review

  • A. Poulton
  • Medicine, Psychology
    Archives of Disease in Childhood
  • 2005
Aims: To get an overview of the studies of growth in height in children with attention deficit hyperactivity disorder (ADHD) treated with stimulant medication, to establish the consistencies and to

Cessation of attention deficit hyperactivity disorder drugs in the young (CADDY)--a pharmacoepidemiological and qualitative study.

The prevalence of prescribing by GPs to patients with ADHD dropped significantly from age 15 to 21, and the fall in prescribing was greater than the reported age-related decrease in symptoms, raising the possibility that treatment is prematurely discontinued in some young adults where ADHD symptoms persist.

Medication holidays.

  • R. Howland
  • Medicine, Biology
    Journal of psychosocial nursing and mental health services
  • 2009
To partially reverse the physiological adaptive effects that result from chronic pharmacological stimulation, medication holidays have been hypothesized to "resensitize" neurons to the acute pharmacological effects of a drug.

Moderators and mediators of long-term adherence to stimulant treatment in children with ADHD.

Adherence to stimulant medications is a significant factor in the long-term treatment of children with ADHD and response to treatment at school, measured at 12 months, was investigated as a mediation of adherence.

ADHD treatment with once-daily OROS methylphenidate: final results from a long-term open-label study.

Sustained effectiveness of OROS MPH was maintained for up to 24 months with minimal effects on growth, tics, vital Signs, vital signs, or laboratory test values, according to parent and investigator assessments.

Methylphenidate: Use in Daily Practice

The percentage of children having a good compliance calculated on the basis of pharmacy records is rather low, partly the result of the decreased use of methylphenidate in the weekends and holidays.

Continuity of methylphenidate treatment for attention-deficit/hyperactivity disorder.

Extended-release MPH formulations were associated with greater continuity of MPH treatment than IR formulations in the study population and initial selection of an ER formulation may help to prolong continuity of MPH therapy among youth Medicaid beneficiaries with attention-deficit/hyperactivity disorder.

Impact of long-term treatment of methylphenidate on height and weight of school age children with ADHD.

A small but significant deceleration of height velocity has been identified as a long-term side effect of methylphenidate, and the magnitude of the height deficit is related to the duration of treatment.