Drug-Eluting Stent Design is a Determinant of Drug Concentration at the Endothelial Cell Surface

Abstract

Although drug-eluting stents (DES) have greatly reduced arterial restenosis, there are persistent concerns about stent thrombosis. DES thrombosis is attributable to retarded vascular re-endothelialization due to both stent-induced flow disturbance and the inhibition by the eluted drug of endothelial cell proliferation and migration. The present… (More)
DOI: 10.1007/s10439-015-1531-0

Topics

8 Figures and Tables

Slides referencing similar topics