Drug Burden Index and change in cognition over time in community-dwelling older men: the CHAMP study.

Abstract

OBJECTIVE Anticholinergic and sedative medications are associated with acute cognitive impairment, but the long-term impact on change in cognition is unclear. This study investigated the effect of anticholinergic and sedative medications, quantified using the Drug Burden Index (DBI), on change in cognition over time in community-dwelling older men… (More)
DOI: 10.1080/07853890.2016.1252053

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