Drug Addiction Endophenotypes: Impulsive Versus Sensation-Seeking Personality Traits

@inproceedings{Ersche2010DrugAE,
  title={Drug Addiction Endophenotypes: Impulsive Versus Sensation-Seeking Personality Traits},
  author={Karen D. Ersche and Abigail J. Turton and Shachi Pradhan and Edward T. Bullmore and Trevor W. Robbins},
  booktitle={Biological Psychiatry},
  year={2010}
}
BACKGROUND Genetic factors have been implicated in the development of substance abuse disorders, but the role of pre-existing vulnerability in addiction is still poorly understood. Personality traits of impulsivity and sensation-seeking are highly prevalent in chronic drug users and have been linked with an increased risk for substance abuse. However, it has not been clear whether these personality traits are a cause or an effect of stimulant drug dependence. METHOD We compared self-reported… CONTINUE READING
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