Drospirenone with 17β-estradiol in the postmenopausal woman with hypertension

  title={Drospirenone with 17$\beta$-estradiol in the postmenopausal woman with hypertension},
  author={William B. White},
  pages={25 - 31}
  • W. White
  • Published 1 January 2007
  • Medicine, Biology
  • Climacteric
Hypertension is one of the most important risk factors for the development of cardiovascular disease. The prevalence of hypertension increases with age and also after the menopause; therefore, blood pressure monitoring and effective control of elevated blood pressure are very important in postmenopausal women. The knowledge that aldosterone is a dual cardiovascular and endocrine hormone has blurred the once distinct boundary between gynecology and cardiovascular medicine. Aldosterone plays a… 

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The results indicate that central estrogen plays a protective role in the development of Aldo/NaCl-induced hypertension and that this may result from reduced sympathetic outflow.

Effect of aerobic exercise on blood lipid levels in postmenopausal women

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Characteristics of nasal epithelial cells in naturally postmenopausal women receiving hormone therapy with 1 mg 17&bgr;-estradiol and 2 mg drospirenone: a prospective study

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Climacteric Commentaries

Commentary on sex steroids being made intracellularly in peripheral tissues by the mechanism of intracrinology after menopause and a calcium-collagen chelate dietary supplement for attenuation of bone loss in postmenopausal women with osteopenia.

Prospective study evaluating olfactometric and rhinomanometric outcomes in postmenopausal women on 1 mg 17&bgr;-estradiol and 2 mg drospirenone HT

It is confirmed that the nasal airflow resistance and olfactory thresholds to odors may depend on steroid hormones, and it is believed that estrogens could influence neuronal plasticity and the neuronal conduction time in the Olfactory system.

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  • E. Conaway
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    The Journal of the American Osteopathic Association
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Bioidentical hormones that are approved by the FDA may be preferred over standard hormone replacement because of their physiologic benefits and safety profile.

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The evidence regarding risk factors for recurrence that might influence the decision to recommend prolonged anticoagulant therapy after a first episode of venous thromboembolism is reviewed, and the implications for practice are considered.



Effects of a New Hormone Therapy, Drospirenone and 17-&bgr;-Estradiol, in Postmenopausal Women With Hypertension

Data show that DRSP combined with E2 significantly reduces BP in postmenopausal women with hypertension and did not induce significant increases in serum potassium, which may lead to a new benefit for this novel hormone therapy in postwomen's hypertension.

Antihypertensive Effects of Drospirenone With 17&bgr;-Estradiol, a Novel Hormone Treatment in Postmenopausal Women With Stage 1 Hypertension

Combination therapy with DRSP/E2 significantly lowered both clinic and 24-hour systolic BP in postmenopausal women with stage 1 systolics hypertension, which may lead to benefit for cardiovascular risk reduction in this population of women.

Interactions of High Salt Intake and the Response of the Cardiovascular System to Aldosterone

  • P. Conlin
  • Biology, Medicine
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  • 2005
Aldosterone blockade with mineralocorticoid receptor antagonists offers target organ protection and may blunt some of the adverse effects of chronic high salt intake.

The influence of menopause on blood pressure.

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