• DOI:10.1016/0010-7824(94)00015-O
Corpus ID: 29979524

Drospirenone: a novel progestogen with antimineralocorticoid and antiandrogenic activity. Pharmacological characterization in animal models.

@article{Muhn1995DrospirenoneAN,
  title={Drospirenone: a novel progestogen with antimineralocorticoid and antiandrogenic activity. Pharmacological characterization in animal models.},
  author={Peter Muhn and R. Krattenmacher and S. Beier and W. Elger and E. Schillinger},
  journal={Contraception},
  year={1995},
  volume={51 2},
  pages={
          99-110
        }
}

Peter Muhn, R. Krattenmacher, +2 authors E. Schillinger

Published 1995

Medicine

Contraception

Drospirenone (ZK 30595; 6 beta, 7 beta, 15 beta, 16 beta-dimethylen-3- oxo-17 alpha-pregn-4-ene-21, 17-carbo-lactone) is a novel progestogen under clinical development. Potential applications include oral contraception, hormone replacement therapy and treatment of hormonal disorders. Drospirenone is characterized by a pharmacodynamic profile very closely related to that of progesterone. The progestogenic activity of drospirenone has been analysed in a variety of animal models. The compound… CONTINUE READING

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