Drospirenone: a novel progestin

@article{Rapkin2007DrospirenoneAN,
  title={Drospirenone: a novel progestin},
  author={Andrea Rapkin and Sharon A. Winer},
  journal={Expert Opinion on Pharmacotherapy},
  year={2007},
  volume={8},
  pages={989 - 999}
}
  • A. RapkinS. Winer
  • Published 1 May 2007
  • Medicine, Biology
  • Expert Opinion on Pharmacotherapy
Drospirenone is a novel progestin available in combined oral contraceptives and menopausal hormonal therapy. Similar to its parent compound spirolactone, an analog of spironolactone, drospirenone has antimineralocorticoid and antiandrogenic activity. Combined with ethinyl estradiol in oral contraceptive formulations, drospirenone-containing contraceptives have similar efficacy and safety profiles to other low-dose oral contraceptives, but seem to offer improved tolerability with regard to… 

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