• DOI:10.1111/j.1749-6632.1995.tb31386.x
Corpus ID: 36861309

Drospirenone: a Novel Progestogen with Antimineralocorticoid and Antiandrogenic Activity

@article{Muhn1995DrospirenoneAN,
  title={Drospirenone: a Novel Progestogen with Antimineralocorticoid and Antiandrogenic Activity},
  author={P. Muhn and U. Fuhrmann and K. Fritzemeier and R. Krattenmacher and E. Schillinger},
  journal={Annals of the New York Academy of Sciences},
  year={1995},
  volume={761}
}

• P. Muhn, U. Fuhrmann, +2 authors E. Schillinger
• Published 1995
• Chemistry, Medicine
• Annals of the New York Academy of Sciences

Drospirenone (ZK 30595; 6 beta, 7 beta, 15 beta, 16 beta-dimethylen-3-oxo-17 alpha-pregn-4-ene-21, 17-carbolactone) is a novel progestogen under clinical development. Drospirenone is characterized by an innovative pharmacodynamic profile which is very closely related to that of progesterone. Potential applications include oral contraception, hormone replacement therapy and treatment of hormonal disorders. The pharmacological properties of drospirenone were investigated in vitro by receptor… Expand