Drospirenone/ethinyl estradiol.

  title={Drospirenone/ethinyl estradiol.},
  author={Andrea J Rapkin and Shelley N Sorger and Sharon A Winer},
  journal={Drugs of today},
  volume={44 2},
Drospirenone 3 mg/ethinyl estradiol 20 microg (24/4) is a new unique oral contraceptive formulation that combines in a novel dosing regimen the lowest dosage of ethinyl estradiol commonly used today with drospirenone, an innovative progestin. Drospirenone is a compound closely resembling progesterone, but with the antimineralocorticoid and antiandrogenic properties of a related therapeutic agent, the diuretic, antihypertensive and androgen receptor antagonist, 17alpha-spironolactone. The… Expand
Beyaz®: An Oral Contraceptive Fortified with Folate
The folate-containing pill may aid in reducing the risk of neural tube defects in a pregnancy conceived during use or shortly after the discontinuation of the product. Expand
Comparative analysis of the effects of nomegestrol acetate/17 β-estradiol and drospirenone/ethinylestradiol on premenstrual and menstrual symptoms and dysmenorrhea
NOMAC/E2 was effective in reducing most premenstrual and menstrual symptoms, and was associated with significantly greater improvements in many MDQ-C domain scores compared with DRSP/EE. Expand
Contraceptive options for women with premenstrual dysphoric disorder: current insights and a narrative review
Oral combined hormonal contraceptives that contain drospirenone in a 24+4-day regimen are the only drugs that have been approved by US Food and Drug Administration for the treatment of PMDD, but there is scientific evidence that other agents, with other formulations and regimens, could also be effective for the Treatment of this condition. Expand
Clinical and metabolic effects of drospirenone–estradiol in menopausal women: a prospective study
In postmenopausal women, E2++DRSP administration improves vasomotor symptoms and general aspects of quality of life and may positively influence cardiovascular risk factors. Expand
Effects of synthetic gestagens on fish reproduction.
The effects of two progestins currently marketed in contraceptive formulations, levonorgestrel (LNG) and drospirenone (DRSP), were investigated in adult fathead minnows following an Organization for Economic Cooperation and Development 21-d fish reproduction screening assay draft protocol with additional end points. Expand
Suppression of ovarian function by a combined oral contraceptive containing 0.02 mg ethinyl estradiol and 2 mg chlormadinone acetate given in a 24/4-day intake regimen over three cycles.
Follicular development, cervical reaction, and endometrial thickness were suppressed profoundly after 0.02 mg ethinyl E(2)-2 mg chlormadinone acetate administration in a 24/4-day regimen, resulting in inhibition of ovulation and unfavorable conditions for fertilization, implantation, and thus pregnancy. Expand
Conventional vs. extended-cycle oral contraceptives on the quality of sexual life: comparison between two regimens containing 3 mg drospirenone and 20 µg ethinyl estradiol.
Women could use OCs in a subjective flexible modality and the extended-cycle OC might produce positive effects on the quality of sexual life, enforcing the concept of tailoring an OC to a woman. Expand
Use of oral contraceptives for management of acne vulgaris and hirsutism in women of reproductive and late reproductive age
Hormonal contraception in both reproductive and late reproductive age, as well as contraceptive action, is used also for other indications like dysmenorrhoea, menstrual disorders, endometriosis, acneExpand
Depression in reproductive-age women: Assessment of infectious, endocrinological, and immunological correlates from an evolutionary perspective
This thesis examined whether depression status in subjects was correlated with infection and medication use and found that the use of exogenous estrogen through oral contraceptive pills (OCPs) could increase depressive symptoms, while theUse of antibiotics to treat C. trachomatis infection could decrease depression. Expand
Acne Treatment Cases with Hwangryeonhaedok-tang
Hwangryeonhaedok-Tang is an antiinflammatory, antipyretic and detoxifying herb decoction used in acne treatment and may be considered as a good prescription for the febrile and toxic type of acne patients. Expand