Drosophila type II neuroblast lineages keep Prospero levels low to generate large clones that contribute to the adult brain central complex

@inproceedings{Bayraktar2010DrosophilaTI,
  title={Drosophila type II neuroblast lineages keep Prospero levels low to generate large clones that contribute to the adult brain central complex},
  author={Omer Ali Bayraktar and Jason Q. Boone and Michael L. Drummond and Chris Q Doe},
  booktitle={Neural Development},
  year={2010}
}
Tissue homeostasis depends on the ability of stem cells to properly regulate self-renewal versus differentiation. Drosophila neural stem cells (neuroblasts) are a model system to study self-renewal and differentiation. Recent work has identified two types of larval neuroblasts that have different self-renewal/differentiation properties. Type I neuroblasts bud off a series of small basal daughter cells (ganglion mother cells) that each generate two neurons. Type II neuroblasts bud off small… CONTINUE READING

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