Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria.

@article{Rmet2001DrosophilaSR,
  title={Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria.},
  author={Mika R{\"a}met and Alex Pearson and Pascal Manfruelli and Xiaoxia Li and Henry Koziel and Verena G{\"o}bel and Eunsook Chung and Monty Krieger and Raymond Alan Brian Ezekowitz},
  journal={Immunity},
  year={2001},
  volume={15 6},
  pages={
          1027-38
        }
}
One hallmark of innate immunity apparently conserved from primitive life forms through to humans is the ability of the host to recognize pathogen-associated molecular patterns (PAMPs). Since macrophage pattern recognition receptors are not well defined in Drosophila, we set out to identify such receptors. Our findings reveal that Drosophila macrophages express multiple pattern recognition receptors and that the Drosophila scavenger receptor, dSR-CI, is one such receptor capable of recognizing… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 115 CITATIONS, ESTIMATED 87% COVERAGE

Scavenger receptor C promotes bacterial clearance in kuruma shrimp Marsupenaeus japonicus by enhancing hemocyte phagocytosis and AMP expression.

Ming-Chong Yang, Hui-Ting Yang, +7 authors Jin-Xing Wang
  • Fish & shellfish immunology
  • 2017
VIEW 5 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Functional Characterization of the Infection-Inducible Peptide Edin in Drosophila melanogaster

Leena-Maija Vanha-aho, Anni Kleino, +5 authors Mika Rämet
  • PloS one
  • 2012
VIEW 3 EXCERPTS
CITES METHODS & BACKGROUND

FILTER CITATIONS BY YEAR

2002
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations