Drosophila melanogaster RECQ5/QE DNA helicase: stimulation by GTP binding.

  title={Drosophila melanogaster RECQ5/QE DNA helicase: stimulation by GTP binding.},
  author={Katsumi Kawasaki and Sayako Maruyama and Minoru Nakayama and Kohji Matsumoto and Takehiko Shibata},
  journal={Nucleic acids research},
  volume={30 17},
The Drosophila melanogaster RECQ5/QE gene encodes a member of the DNA helicase family comprising the Escherichia coli RecQ protein and products of the human Bloom's, Werner's, and Rothmund-Thomson syndrome genes. The full-length product of RECQ5/QE was expressed in the baculovirus system and was purified. Gel filtration experiments indicated that RECQ5/QE was present in an oligomeric state. The RECQ5/QE protein hydrolyzed ATP and even more actively GTP in the presence of single-stranded DNA… CONTINUE READING
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Identi®cation of Drosophila melanogaster RECQE as a member of a new family of RecQ homologues preferentially expressed in early embryos

  • Jeong, S.-M, K. Kawasaki, N. Juni, T. Shibata
  • Mol. Gen. Genet.,
  • 2000

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