Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity

  title={Drosophila melanogaster Models of Metal-Related Human Diseases and Metal Toxicity},
  author={Pablo Calap-Quintana and Javier Gonz{\'a}lez-Fern{\'a}ndez and Noelia Sebastia-Ortega and Jose Vicente Llorens and Mar{\'i}a Dolores Molt{\'o}},
  booktitle={International journal of molecular sciences},
Iron, copper and zinc are transition metals essential for life because they are required in a multitude of biological processes. Organisms have evolved to acquire metals from nutrition and to maintain adequate levels of each metal to avoid damaging effects associated with its deficiency, excess or misplacement. Interestingly, the main components of metal homeostatic pathways are conserved, with many orthologues of the human metal-related genes having been identified and characterized in… CONTINUE READING
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