Drosophila male germline stem cells do not asymmetrically segregate chromosome strands.

@article{Yadlapalli2011DrosophilaMG,
  title={Drosophila male germline stem cells do not asymmetrically segregate chromosome strands.},
  author={Swathi Yadlapalli and Jun Cheng and Yukiko M Yamashita},
  journal={Journal of cell science},
  year={2011},
  volume={124 Pt 6},
  pages={933-9}
}
Adult stem cells continuously supply differentiated cells throughout the life of organisms. This increases the risk of replicative senescence or neoplastic transformation due to mutations that accumulate over many rounds of DNA replication. The immortal strand hypothesis proposes that stem cells reduce the accumulation of replication-induced mutations by retaining the older template DNA strands. Other models have also been proposed in which stem cells asymmetrically segregate chromosome strands… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 23 extracted citations

Similar Papers

Loading similar papers…