Drosophila lacking microRNA miR-278 are defective in energy homeostasis.

@article{Teleman2006DrosophilaLM,
  title={Drosophila lacking microRNA miR-278 are defective in energy homeostasis.},
  author={Aurelio A Teleman and Sushmita Maitra and Stephen Michael Cohen},
  journal={Genes & development},
  year={2006},
  volume={20 4},
  pages={417-22}
}
The mechanisms that control energy homeostasis and tissue growth during development are closely linked through the insulin signal transduction pathway. Changes in the level of insulin and other hormones reflect the nutritional status of the animal to control circulating sugar levels and fat metabolism. Systemic defects in insulin responsiveness can lead to elevated circulating glucose levels and fat accumulation. Here we present evidence that the microRNA miR-278 plays a role in the control of… CONTINUE READING