Drosophila hedgehog signaling and engrailed-runt mutual repression direct midline glia to alternative ensheathing and non-ensheathing fates

  title={Drosophila hedgehog signaling and engrailed-runt mutual repression direct midline glia to alternative ensheathing and non-ensheathing fates},
  author={Joseph D. Watson and Scott R. Wheeler and S. B. Stagg and S. Crews},
  pages={1285 - 1295}
  • Joseph D. Watson, Scott R. Wheeler, +1 author S. Crews
  • Published 2011
  • Biology, Medicine
  • Development
  • The Drosophila CNS contains a variety of glia, including highly specialized glia that reside at the CNS midline and functionally resemble the midline floor plate glia of the vertebrate spinal cord. Both insect and vertebrate midline glia play important roles in ensheathing axons that cross the midline and secreting signals that control a variety of developmental processes. The Drosophila midline glia consist of two spatially and functionally distinct populations. The anterior midline glia (AMG… CONTINUE READING
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