Drosophila development: A prepattern for sensory organs

@article{Simpson1996DrosophilaDA,
  title={Drosophila development: A prepattern for sensory organs},
  author={Pat Simpson},
  journal={Current Biology},
  year={1996},
  volume={6},
  pages={948-950}
}
  • P. Simpson
  • Published 1 August 1996
  • Biology
  • Current Biology
View on Elsevier
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26 Citations
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26 Citations

Sense organ identity in the Drosophila antenna is specified by the expression of the proneural gene atonal
Notch signalling in development: on equivalence groups and asymmetric developmental potential.
  • P. Simpson
  • Biology
    Current opinion in genetics & development
  • 1997
How to pattern an epithelium: lessons from achaete-scute regulation on the notum of Drosophila.
Prepatterning the Drosophila notum: the three genes of the iroquois complex play intrinsically distinct roles.
Regulation of dally, an integral membrane proteoglycan, and its function during adult sensory organ formation of Drosophila.
TLDR
Dally is established as an important regulator of sensory organ formation via Wg- and Dpp-mediated specification of proneural clusters for dally-sensitive bristles and shows genetic interactions with either wg or dpp signaling components for distinct sensory bristles.
Genetic analysis of bristle loss in hybrids between Drosophila melanogaster and D. simulans provides evidence for divergence of cis-regulatory sequences in the achaete-scute gene complex.
TLDR
Evidence is provided that bristle loss in the hybrids may result from a decrease in the level of transcription at the achaete-scute complex (AS-C), and it is argued that interaction between trans-acting factors and cis-regulatory elements within the AS-C has diverged between the two species.
Expression of achaete-scute homologues in discrete proneural clusters on the developing notum of the medfly Ceratitis capitata, suggests a common origin for the stereotyped bristle patterns of higher Diptera.
TLDR
At least three genes, scute, lethal of scute and asense have been conserved, thus demonstrating that gene duplication within the achaete-scute complex preceded the separation of the families Drosophilidae and Tephritidae, whose common ancestor goes back more than 100 million years.
Irregular chiasm-C-roughest, a member of the immunoglobulin superfamily, affects sense organ spacing on the Drosophila antenna by influencing the positioning of founder cells on the disc ectoderm
TLDR
It is proposed that IrreC-rst affects the spatial relationship between sensory and ectodermal cells during FC delamination, which results in an altered arrangement of FCs within the disc compared to wildtype.
Probing the dynamics of cell di erentiation in a model of DrosophilaneurogenesisGeorge
TLDR
A computational model is formulated of Drosophila early neurogenesis, the process by which neu-roblasts and sensory organ precursor cells differentiate from within proneural clusters of cells, which includes intracellular gene regulatory interactions as well as lateral cell-cell signalling.
Role of dpp signalling in prepattern formation of the dorsocentral mechanosensory organ in Drosophila melanogaster.
TLDR
The results suggest that Dpp signalling has two indispensable roles in dorsocentrals bristle formation: induction of the dorsocentral proneural cluster in cooperation with Wg signalling and restriction of the wg expression domain in the notum region of the wing imaginal disc.
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References

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