Drosophila comet assay: insights, uses, and future perspectives

@inproceedings{Gaivo2014DrosophilaCA,
  title={Drosophila comet assay: insights, uses, and future perspectives},
  author={Isabel Gaiv{\~a}o and Luisa Maria Sierra},
  booktitle={Front. Genet.},
  year={2014}
}
The comet assay, a very useful tool in genotoxicity and DNA repair testing, is being applied to Drosophila melanogaster since around 15 years ago, by several research groups. This organism is a valuable model for all kind of processes related to human health, including DNA damage response. The assay has been performed mainly in vivo using different larvae cell types (from brain, midgut, hemolymph, and imaginal disk), but also in vitro with the S2 cell line. Since its first application, it has… CONTINUE READING
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Comet assay: an essential tool in toxicological research

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