Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye.

@article{Thomas1998DrosophilaBI,
  title={Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye.},
  author={Graham H. Thomas and Daniela C. Zarnescu and Amy E. Juedes and Mark A. Bales and Amy Londergan and Carol C. Korte and Daniel P Kiehart},
  journal={Development},
  year={1998},
  volume={125 11},
  pages={2125-34}
}
The spectrin membrane skeleton is a ubiquitous cytoskeletal structure with several cellular roles, including the maintenance of cell integrity, determination of cell shape and as a contributor to cell polarity. We have isolated mutations in the gene encoding &bgr ;Heavy-spectrin in Drosophila, and have named this essential locus karst. karst mutant… CONTINUE READING