Drosophila TRPA1 Channel Is Required to Avoid the Naturally Occurring Insect Repellent Citronellal

@article{Kwon2010DrosophilaTC,
  title={Drosophila TRPA1 Channel Is Required to Avoid the Naturally Occurring Insect Repellent Citronellal},
  author={Young Hee Kwon and Sang Hoon Kim and David S. Ronderos and Youngseok Lee and Bradley Akitake and Owen M Woodward and William B Guggino and Dean Smith and Craig Montell},
  journal={Current Biology},
  year={2010},
  volume={20},
  pages={1672-1678}
}
Plants produce insect repellents, such as citronellal, which is the main component of citronellal oil. However, the molecular pathways through which insects sense botanical repellents are unknown. Here, we show that Drosophila use two pathways for direct avoidance of citronellal. The olfactory coreceptor OR83b contributes to citronellal repulsion and is essential for citronellal-evoked action potentials. Mutations affecting the Ca(2+)-permeable cation channel TRPA1 result in a comparable defect… CONTINUE READING
BETA

Figures and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 64 CITATIONS, ESTIMATED 33% COVERAGE

FILTER CITATIONS BY YEAR

2010
2018

CITATION STATISTICS

  • 7 Highly Influenced Citations

  • Averaged 11 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 34 REFERENCES

Similar Papers

Loading similar papers…