Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.

@article{Yokomori1993DrosophilaTI,
  title={Drosophila TFIIA-L is processed into two subunits that are associated with the TBP/TAF complex.},
  author={Kyoko Yokomori and Arie Admon and James A. Goodrich and Jacky Chen and Robert Tjian},
  journal={Genes & development},
  year={1993},
  volume={7 11},
  pages={2235-45}
}
The basal factor TFIIA has been shown to act early during initiation in both the mammalian and yeast transcription systems, but a TFIIA-like activity has not been identified in Drosophila. While characterizing the Drosophila TFIID complex, we discovered that a 30-kD protein that cofractionated with dTFIID was homologous to the previously identified, large subunit of yeast TFIIA. Here, we report the cloning and biochemical characterization of Drosophila TFIIA-L. Coimmunoprecipitation studies… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Transcription, GeneticProcess includes biological processTranscription Initiation
These results suggest that TFIIA may form a specific complex with both TAFs and other components of the transcriptional machinery during formation of the initiation complex .
These results suggest that TFIIA may form a specific complex with both TAFs and other components of the transcriptional machinery during formation of the initiation complex .
While characterizing the Drosophila TFIID complex , we discovered that a 30-kD protein that cofractionated with dTFIID was homologous to the previously identified , large subunit of yeast TFIIA .
While characterizing the Drosophila TFIID complex , we discovered that a 30-kD protein that cofractionated with dTFIID was homologous to the previously identified , large subunit of yeast TFIIA .
Transcription Factor TFIIAGene product plays role in biological processTranscription Initiation
The basal factor TFIIA has been shown to act early during initiation in both the mammalian and yeast transcription systems , but a TFIIA - like activity has not been identified in Drosophila .
These results suggest that TFIIA may form a specific complex with both TAFs and other components of the transcriptional machinery during formation of the initiation complex .
The basal factor TFIIA has been shown to act early during initiation in both the mammalian and yeast transcription systems , but a TFIIA - like activity has not been identified in Drosophila .
All Topics