Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology.

@article{Nagai2010DrosophilaSA,
  title={Drosophila Syntrophins are involved in locomotion and regulation of synaptic morphology.},
  author={Rika Nagai and Reina Hashimoto and Masamitsu Yamaguchi},
  journal={Experimental cell research},
  year={2010},
  volume={316 14},
  pages={2313-21}
}
Syntrophin components of the dystrophin glycoprotein complex (DGC) feature multiple protein interaction domains that may act in molecular scaffolding, recruiting signaling proteins to membranes and the DGC. Drosophila Syntrophin-1 (Syn1) and Syntrophin-2 (Syn2) are counterparts of human alpha1/beta1/beta2-syntrophins and gamma1/gamma2-syntrophins, respectively. alpha1/beta1/beta2-syntrophins are well documented, while little is known about gamma1/gamma2-syntrophins. Here, we performed… CONTINUE READING