Drosophila Muscleblind Is Involved in troponin T Alternative Splicing and Apoptosis

Abstract

BACKGROUND Muscleblind-like proteins (MBNL) have been involved in a developmental switch in the use of defined cassette exons. Such transition fails in the CTG repeat expansion disease myotonic dystrophy due, in part, to sequestration of MBNL proteins by CUG repeat RNA. Four protein isoforms (MblA-D) are coded by the unique Drosophila muscleblind gene… (More)
DOI: 10.1371/journal.pone.0001613

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@article{VicenteCrespo2008DrosophilaMI, title={Drosophila Muscleblind Is Involved in troponin T Alternative Splicing and Apoptosis}, author={Marta Vicente-Crespo and M. de Zulueta Pascual and Juan M. Fernandez-Costa and Amparo Garc{\'i}a-L{\'o}pez and Lid{\'o}n Monferrer and Marta Miranda and Lei Zhou and Rub{\'e}n Artero}, journal={PLoS ONE}, year={2008}, volume={3}, pages={1140 - 1147} }