Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm.

@article{Tanaka2011DrosophilaMC,
  title={Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm.},
  author={Tsubasa Tanaka and Yasuko Kato and Kazuki Matsuda and Kazuko Hanyu-Nakamura and Akira Nakamura},
  journal={Development},
  year={2011},
  volume={138 12},
  pages={2523-32}
}
Drosophila pole (germ) plasm contains germline and abdominal determinants. Its assembly begins with the localization and translation of oskar (osk) RNA at the oocyte posterior, to which the pole plasm must be restricted for proper embryonic development. Osk stimulates endocytosis, which in turn promotes actin remodeling to form long F-actin projections at the oocyte posterior pole. Although the endocytosis-coupled actin remodeling appears to be crucial for the pole plasm anchoring, the… CONTINUE READING
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