Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation

Abstract

BACKGROUND Recent research supports that aggregation of islet amyloid polypeptide (IAPP) leads to cell death and this makes islet amyloid a plausible cause for the reduction of beta cell mass, demonstrated in patients with type 2 diabetes. IAPP is produced by the beta cells as a prohormone, and proIAPP is processed into IAPP by the prohormone convertases… (More)
DOI: 10.1371/journal.pone.0020221

Topics

9 Figures and Tables

Cite this paper

@inproceedings{Schultz2011DrosophilaMA, title={Drosophila Melanogaster as a Model System for Studies of Islet Amyloid Polypeptide Aggregation}, author={Sebastian Wolfgang Schultz and K Peter R Nilsson and Gunilla Torstensdotter Westermark}, booktitle={PloS one}, year={2011} }