Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription.

@article{Andersen2010DrosophilaMA,
  title={Drosophila MCRS2 associates with RNA polymerase II complexes to regulate transcription.},
  author={Ditte Skovaa Andersen and Sunil Jayaramaiah Raja and Julien Colombani and Rachael Louise Shaw and Paul Francis Langton and Asifa Akhtar and Nicolas Tapon},
  journal={Molecular and cellular biology},
  year={2010},
  volume={30 19},
  pages={4744-55}
}
Drosophila MCRS2 (dMCRS2; MCRS2/MSP58 and its splice variant MCRS1/p78 in humans) belongs to a family of forkhead-associated (FHA) domain proteins. Whereas human MCRS2 proteins have been associated with a variety of cellular processes, including RNA polymerase I transcription and cell cycle progression, dMCRS2 has been largely uncharacterized. Recent data show that MCRS2 is purified as part of a complex containing the histone acetyltransferase MOF (males absent on first) in both humans and… CONTINUE READING