Drosophila GoLoco-protein Pins as a target of Gαo-mediated G protein coupled receptor signaling

@inproceedings{Kopein2009DrosophilaGP,
  title={Drosophila GoLoco-protein Pins as a target of Gαo-mediated G protein coupled receptor signaling},
  author={DS Kopein and Kay Diederichs and VL Katanaev},
  booktitle={Cell Communication and Signaling},
  year={2009}
}
Heterotrimeric G-proteins are molecular switches that regulate numerous aspects of cellular physiology by transducing the signals from G protein-coupled receptors (GPCRs). In the basal state, the Gα-subunits of the heterotrimeric G proteins are GDP-liganded (the inactive form) and bind to the βγ-complex. GPCRs can activate guanine nucleotide exchange on the… CONTINUE READING