Drosophila CLAMP is an essential protein with sex-specific roles in males and females

@inproceedings{Urban2016DrosophilaCI,
  title={Drosophila CLAMP is an essential protein with sex-specific roles in males and females},
  author={Jennifer A Urban and Caroline A. Doherty and William T. Jordan and Jacob E. Bliss and Jessica Feng and Marcela M. L. Soruco and Leila E. Rieder and Erica Larschan},
  year={2016}
}
Dosage compensation is a fundamental mechanism in many species that corrects for the inherent imbalance in X-chromosome copy number between XY males and XX females. In Drosophila melanogaster, transcriptional output from the single male X-chromosome is equalized to that of XX females by recruitment of the Male Specific Lethal (MSL) complex to specific… CONTINUE READING